How a controversial US drug policy could be harming cancer patients worldwide

Cancer drugs on the go: Graphic showing the amount and status of cancer drugs given accelerated approval since 1995.

In August 2021, Amol Akhade, an oncologist at Nair Medical Hospital in Mumbai, India, received an e-mail from the Swiss drug manufacturer Roche recommending the use of a drug named atezolizumab to treat a specific kind of breast cancer. Akhade was surprised. That month, Roche had withdrawn the drug for this purpose in the United … Read more

Debunking Myths: Depression, Anxiety, and Cancer Risk

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Depression and anxiety are not significantly linked to higher cancer risks for most types, according to a multinational study. While a slight increase in risk was observed for lung and smoking-related cancers among those with depression or anxiety, this was largely mitigated by adjustments for lifestyle factors. Recent research indicates that depression and anxiety do … Read more

Colorado cancer centers try to manage chemotherapy drug shortage

Colorado cancer centers try to manage chemotherapy drug shortage

In this May 25, 2017 file photo, chemotherapy drugs are administered to a patient at a hospital in Chapel Hill, N.C. Two workhorse chemotherapy drugs are increasingly hard to come by, and Colorado cancer centers are trying to manage the shortages with as little effect on patients as possible. A May survey of 27U.S. cancer … Read more

FDA Approves LONSURF (trifluridine/tipiracil) in Combination With Bevacizumab for Adult Patients With Metastatic Colorectal Cancer (mCRC)

FDA Approves LONSURF (trifluridine/tipiracil) in Combination With Bevacizumab for Adult Patients With Metastatic Colorectal Cancer (mCRC)

Approval is based on data from a pivotal clinical trial showing that treatment with LONSURF plus bevacizumab resulted in statistically significant and clinically meaningful improvements in overall survival in patients with previously treated mCRC compared to LONSURF as a single agent PRINCETON, N.J., Aug. 2, 2023 /PRNewswire/ — Taiho Oncology, Inc. and Taiho Pharmaceutical Co., Ltd. … Read more

FDA Approves Trifluridine/Tipiracil Plus Bevacizumab in Previously Treated Metastatic Colorectal Cancer

FDA Approves Trifluridine/Tipiracil Plus Bevacizumab in Previously Treated Metastatic Colorectal Cancer

The FDA has approved trifluridine and tipiracil (Lonsurf) plus bevacizumab (Avastin) for patients with metastatic colorectal cancer (mCRC) who were previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy; a VEGF inhibitor; and an EGFR inhibitor, if they have RAS wild-type disease.1,2 The regulatory decision is supported by data from the phase 3 SUNLIGHT trial (NCT04737187), … Read more

Addition of Talazoparib to Enzalutamide in the First-Line Treatment of Metastatic Castration-Resistant Prostate Cancer

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By Matthew Stenger Posted: 8/2/2023 12:07:00 PM Last Updated: 8/2/2023 11:23:29 AM As reported in The Lancet by Neeraj Agarwal, MD, FASCO, and colleagues, the phase III TALAPRO-2 trial has shown that the addition of talazoparib to enzalutamide improved radiographic progressionfree survival vs enzalutamide alone in the first-line treatment of patients with metastatic castration-resistant prostate … Read more

New Science Suggests That Just 4 Minutes Per Day of This Kind of Exercise May Lower Cancer Risk

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Turns out, you could slash your risk for certain cancers in the time it takes to listen to your favorite pop song or power walk across the parking lot. Getty Images Reviewed by Dietitian Annie Nguyen, M.A., RD We’ve been told for decades that walking 10,000 steps per dayor racking up 150 minutes of physical … Read more

FDA Approves Dostarlimab-gxly Plus Chemotherapy for dMMR or MSI-H Endometrial Cancer

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By The ASCO Post Staff Posted: 8/1/2023 9:22:00 AM Last Updated: 8/1/2023 9:48:24 AM On July 31, the U.S. Food and Drug Administration (FDA) approved dostarlimab-gxly (Jemperli) with carboplatin and paclitaxel followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer that is mismatch repairdeficient (dMMR), as determined by an FDA-approved test, … Read more

Study Finds That We Can Reduce Our Cancer Risk Thanks to Vigorous Everyday Activities

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Many people know exercise reduces the risk of cancers, including liver, lung, breast, and kidney. But structured exercise is time-consuming, requires significant commitment, and often financial outlay or travel to a gym. These practicalities can make it infeasible for most adults. There is very little research on the potential of incidental physical activity for reducing … Read more